Alvimopan
爱维莫潘
Catalog No.
A3162
μ-阿片受体拮抗剂
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Alvimopan(ADL 8-2698; Entereg; LY 246736) is a selective and competitive antagonist at mu-opioid receptors, found in myenteric and submucosal neurons and the immune cells of the lamina propria in the human gut. Upon administration, Alvimopan(ADL 8-2698; Entereg; LY 246736) binds to mu-opioid receptors in the gut, thereby reversing opiod-related disturbances in gut motility. Alvimopan is approximately three to nine times more potent than naloxone.A synthetic trans-3,4-dimethyl-4-(3-hydroxyphenyl) piperidine with peripherally selective opioid mu receptor antagonist activity.
| Storage | Store at -20°C |
| M.Wt | 424.53 |
| Cas No. | 156053-89-3 |
| Formula | C25H32N2O4 |
| Synonyms | ADL 8-2698; Entereg; LY 246736 |
| Solubility | insoluble in H2O; insoluble in EtOH; ≥25.7 mg/mL in DMSO |
| Chemical Name | 2-((Z)-((S)-2-benzyl-1-hydroxy-3-((3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)propylidene)amino)acetic acid |
| SDF | Download SDF |
| Canonical SMILES | C[C@@]1([H])CN(C[C@](/C(O)=N/CC(O)=O)([H])CC2=CC=CC=C2)CC[C@]1(C3=CC(O)=CC=C3)C |
| 运输条件 | 蓝冰运输或根据您的需求运输。 |
| 一般建议 | 不同厂家不同批次产品溶解度各有差异，仅做参考。若实验所需浓度过大至产品溶解极限，请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存，请尽快用完。 |
质量控制和MSDS
- 批次:
化学结构
