Acetyl Angiotensinogen (1-14), porcine
mRNA synthesis
In vitro transcription of capped mRNA with modified nucleotides and Poly(A) tail
Tyramide Signal Amplification (TSA)
TSA (Tyramide Signal Amplification), used for signal amplification of ISH, IHC and IC etc.
Phos Binding Reagent Acrylamide
Separation of phosphorylated and non-phosphorylated proteins without phospho-specific antibody
Cell Counting Kit-8 (CCK-8)
A convenient and sensitive way for cell proliferation assay and cytotoxicity assay
SYBR Safe DNA Gel Stain
Safe and sensitive stain for visualization of DNA or RNA in agarose or acrylamide gels.
Inhibitor Cocktails
Protect the integrity of proteins from multiple proteases and phosphatases for different applications.
乙酰血管紧张素原(1-14),猪源,化学式为 C87H125N21O21,序列为AC-ASP-ARG-VAL-Tyr-Ile-HIS-PRO-PHE-HIS-LEU-LEU-VAL-TYR-SER-OH,分子量为1801.05。乙酰血管紧张素原是由血管紧张素原基因编码的蛋白质,又被称为血管紧张素原前体。血压降低时,血管紧张素原前体在肝脏中表达,被肾素酶分解得到产物血管紧张素I,然后被血管紧张素转换酶(ACE)分解,形成具有生理活性的血管紧张素II。血管紧张素II参与维持血压和原发性高血压和先兆子痫的发病机理(2)。该基因的突变与原发性高血压易感性相关,可以引起肾小管发育不全,肾小管发育不全是肾小管发育的失调症。基因中的缺陷也与非家族结构心房颤动和炎性肠病相关。
Figure1 Formula of Acetyl Angiotensinogen (1-14),porcine
Figure2 The renin–angiotensin–aldosterone system
参考文献:
1. Basso N, Terragno NA (December 2001). "History about the discovery of the renin-angiotensin system". Hypertension 38 (6): 1246–9.
2. Skurk T, Lee YM, Hauner H (May 2001). "Angiotensin II and its metabolites stimulate PAI-1 protein release from human adipocytes in primary culture". Hypertension 37 (5): 1336–40.
Physical Appearance | A solid |
Storage | Store at -20°C |
M.Wt | 1801.05 |
Cas No. | 66641-26-7 |
Formula | C87H125N21O21 |
Synonyms | Ac-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-Leu-Val-Tyr-Ser-OH |
Solubility | insoluble in EtOH; insoluble in H2O; ≥180.1 mg/mL in DMSO |
SDF | Download SDF |
Canonical SMILES | CCC(C)C(C(=O)NC(CC1=CN=CN1)C(=O)N2CCCC2C(=O)NC(CC3=CC=CC=C3)C(=O)NC(CC4=CN=CN4)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)NC(C(C)C)C(=O)NC(CC5=CC=C(C=C5)O)C(=O)NC(CO)C(=O)O)NC(=O)C(CC6=CC=C(C=C6)O)NC(=O)C(C(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC(=O)O)NC(=O)C |
运输条件 | 蓝冰运输或根据您的需求运输。 |
一般建议 | 不同厂家不同批次产品溶解度各有差异,仅做参考。若实验所需浓度过大至产品溶解极限,请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存,请尽快用完。 |
质量控制和MSDS
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