Acamprosate calcium
mRNA synthesis
In vitro transcription of capped mRNA with modified nucleotides and Poly(A) tail
Tyramide Signal Amplification (TSA)
TSA (Tyramide Signal Amplification), used for signal amplification of ISH, IHC and IC etc.
Phos Binding Reagent Acrylamide
Separation of phosphorylated and non-phosphorylated proteins without phospho-specific antibody
Cell Counting Kit-8 (CCK-8)
A convenient and sensitive way for cell proliferation assay and cytotoxicity assay
SYBR Safe DNA Gel Stain
Safe and sensitive stain for visualization of DNA or RNA in agarose or acrylamide gels.
Inhibitor Cocktails
Protect the integrity of proteins from multiple proteases and phosphatases for different applications.
阿坎酸钙(acamprosate calcium)是一种戒除酒精依赖患者酒瘾的合成药物[1]。
阿坎酸给药能减少酒精摄入。在大鼠模型中，以50到400 mg/kg/day的剂量口服阿坎酸可剂量依耐性地降低自发性口服乙醇的消耗量。但是，阿坎酸精确的细胞内靶点和机制尚不明确。阿坎酸的结构与GABA结构类似。阿坎酸可与GABAB受体，而非GABAA受体特异性结合。此外，阿坎酸具有血清素的特性。在暴露于乙醇蒸汽的大鼠中，它可以提高5-HT水平蒸汽及5-HT引起的效应。另外，阿坎酸对抑制氨基酸的兴奋性活性和减少Ca2+流有一定的作用。
参考文献：
1. Wilde M I, Wagstaff A J. Acamprosate. Drugs, 1997, 53(6): 1038-1053.
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 400.48 |
| Cas No. | 77337-73-6 |
| Formula | C10H20CaN2O8S2 |
| Synonyms | Calcium N-acetylhomotaurinate; Campral EC |
| Solubility | ≥40 mg/mL in H2O; insoluble in DMSO; insoluble in EtOH |
| Chemical Name | calcium;3-acetamidopropane-1-sulfonate |
| SDF | Download SDF |
| Canonical SMILES | CC(=O)NCCCS(=O)(=O)[O-].CC(=O)NCCCS(=O)(=O)[O-].[Ca+2] |
| 运输条件 | 蓝冰运输或根据您的需求运输。 |
| 一般建议 | 不同厂家不同批次产品溶解度各有差异，仅做参考。若实验所需浓度过大至产品溶解极限，请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存，请尽快用完。 |
质量控制和MSDS
- 批次:
化学结构
