2-Thio-UTP
Catalog No.
B7984
Base modified ribonucleoside triphosphates
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Base modified ribonucleoside triphosphates. RNAs prepared from 2-Thio-UTP is less immunogenic as compared to unmodified RNA. 2-Thio-U modified mRNA shows no activation of RNA-dependent protein kinase, significantly reduced levels of 2'-5'-oligoadenylate synthetase activation, reduced levels of retinoic acid-inducible protein I and suppression of activation of Toll-like receptors.
| Physical Appearance | Solution |
| Storage | Store at -20°C or below |
| M.Wt | 500.2 (free acid) |
| Formula | C9H15N2O14P3S (free acid) |
| Synonyms | 2-Thiouridine-5'-Triphosphate |
| Chemical Name | lithium (3,4-dihydroxy-5-(4-oxo-2-thioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl triphosphate |
| SDF | Download SDF |
| Canonical SMILES | O=C(C=CN1C2C(O)C(O)C(COP([O-])(OP([O-])(OP([O-])([O-])=O)=O)=O)O2)NC1=S.[Li+].[Li+].[Li+].[Li+] |
| 运输条件 | 蓝冰运输或根据您的需求运输。 |
| 一般建议 | 不同厂家不同批次产品溶解度各有差异，仅做参考。若实验所需浓度过大至产品溶解极限，请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存，请尽快用完。 |
化学结构
